Restart slideshow

The Saddest Moments In TV History, Ranked

Prev 15 of 29 Next
#15: Dr. Mark Greene’s Death On ‘ER’
Dr. Greene's death on ER got the audience right in the feels. With his personal life in shambles — where he was divorced from his wife and estranged from his daughter — everything changed for him when he was diagnosed with an aggressive terminal brain tumor.

Knowing he didn't have long to live, he set things right with his family and they went with him on one last family vacation to Hawaii, where he spends his final days. That moment when his daughter slips a pair of head phones over his ears and “Over the Rainbow” starts playing as he drifts off into death will leave you very choked up.